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CAPABILITIES

Our multidisciplinary research team includes experts in epidemiology, clinical research, biological sciences, technology development and optometry, ophthalmology and opticianary – all with relentless and insatiable passion for public health.

Clinical Research and Trial Services

Our Clinical Research and Trials Centre in Sydney is a specialised clinical research facility with capabilities and programs specifically designed to meet the needs of the ophthalmic and vision care industry.

Dedicated clinical research teams aim to identify and understand clinical problems by evaluating the performance of contemporary products.

We have the capacity, technical expertise and experience to generate effective product-based solutions.

Extensive laboratory facilities and the expertise of the scientific team provide a vital adjunct by enabling in-depth evaluation of the interaction between products and the ocular environment.
Activities
Clinical research activities are dedicated to developing and testing products for vision correction, including:
  • Contact lenses
  • Contact lens solutions
  • Spectacles
  • New instruments and techniques.
Standards and guidelines
All optometrists are highly qualified, required to demonstrate concordance at regular intervals, and undergo regular training to maintain and enhance general and specialised optometric skills.

Local and international regulations and guidelines met include:
  • National Statement on Ethical Conduct in Human Research
  • Access to Unapproved Therapeutic Goods
  • Good Clinical Practice
  • Declaration of Helsinki.
Participant populations
In addition to our Sydney clinical trials centre, we have a clinical research facility at Brien Holden Vision Institute China in Guangzhou. We currently have more than 2,500 and 1,200 active participants listed on our Sydney and Guangzhou facilities respectively.

We also have access to overseas collaborators for trials that require special populations or a larger sample size.
FIND OUT MORE: Clinical research and trial services
Clinical Research

Technology - Novel Instruments and Know How

Contact lens metrology
  • Lens parameter measurements in accordance with ISO
  • Visualisation of optical zones and defects using unique Contact Lens Quality Analyser
  • Measuring the shape of soft contact lenses, including base curve profile
  • Assessment of contact lens optical performance for central and peripheral vision using life size model eye.
Developed and validated clinical assessment tools
  • Electronic Vision Charts for distance, intermediate and near
  • Testing of peripheral contrast sensitivity
  • Dynamic vision assessment, i.e. vision after blink
  • Peripheral refraction measurement
Material testing
  • Customised micro-tensometer to measure mechanical properties of contact lens materials under on-eye conditions
  • Determination of equivalent water content
  • Assessing surface wettability using meniscus height and meniscus force methods
  • Spectral transmission and refractive index measurements
  • Hydraulic conductivity of contact lens and related materials
Our novel instruments
  • Optical Quality Analyser (1985)
  • CRCERT-Belmonte Aesthesiometer (2000)
  • Ex Vivo Accommodation Simulator (2005)
  • Eye Tracker (2004)
  • Micro-Tensometer (2004)
  • Model Eye (2011)
  • EyeMapper (2011)
  • OCT Profilometer (2014)
  • Friction Meter (2015)
Improvements
  • Modified Autorefractor (2007)
  • Aberrometer (2009)
  • Measuring Microscope (2013)
Technology and Novel Instruments

Biological Sciences

Our research and product development capabilities are in the core areas of microbiology, biochemistry and molecular biology, including:
  • Diagnostic microbiology
  • Evaluation of antimicrobial efficacy of contact lens care products and hygiene practice
  • Determination of efficacy of novel antimicrobials
  • Biochemical analysis of tears, meibum and contact lens deposits.
Biological Sciences